Anti-HIF-1 β/ARNT antibody

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Product name Anti-HIF-1 β/ARNT antibody
Description Mouse monoclonal to HIF-1 β/ARNT (4C5).
Applications IHC, WB
Dilution range WB 1:1000-2000
IHC 1:100-200
Specificity HIF-1 β/ARNT Mouse Monoclonal Antibody (4C5) detects endogenous levels of HIF-1 β/ARNT
Protein Name Aryl hydrocarbon receptor nuclear translocator
ARNT protein
Class E basic helix-loop-helix protein 2
Dioxin receptor, nuclear translocator
Hypoxia-inducible factor 1-beta
Immunogen Recombinant Protein
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Validated Application IF
Host Mouse
Clonality Monoclonal
Reactivity Mouse
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Isotype IgG1
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 405
Gene Symbol ARNT
Database Links HGNC:700
Alternative Names HIF-1 β/Aryl hydrocarbon receptor nuclear translocator antibody protein antibody
Class E basic helix-loop-helix protein 2 antibody
bHLHe2 antibody
Dioxin receptor, nuclear translocator antibody
Hypoxia-inducible factor 1-beta antibody
HIF-1-beta antibody
HIF1-beta antibody
BHLHE2 antibody
Function Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
Cellular Localization Nucleus.
Swiss-Prot Key P27540_HUMAN
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