Anti-ICAM1 antibody

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Product name Anti-ICAM1 antibody
Short Description Rabbit monoclonal to ICAM1
Description This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
Applications IF, IHC, WB
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Intercellular adhesion molecule 1
ICAM-1
Major group rhinovirus receptor
CD antigen CD54
Immunogen Recombinant protein of human ICAM1
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB IHC IF
Host Rabbit
Clonality Monoclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 3383
Gene Symbol ICAM1
Molecular Weight 57.825 kDa
Database Links HGNC:5344
OMIM:147840
Reactome:R-HSA-198933
Alternative Names Intercellular adhesion molecule 1 antibody
ICAM-1 antibody
Major group rhinovirus receptor antibody
CD antigen CD54 antibody
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2), During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation,
Post-translational Modifications Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis
Cellular Localization Membrane
Swiss-Prot Key P05362
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