Anti-NGFR antibody

[STJ112916] Download PDF Print Data Sheet

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Product name Anti-NGFR antibody
Short Description Rabbit monoclonal to NGFR
Description Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
Applications IF, IHC, IP, WB
Dilution range WB 1:10000 - 1:20000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:20 - 1:50
Protein Name Tumor necrosis factor receptor superfamily member 16
Gp80-LNGFR
Low affinity neurotrophin receptor p75NTR
Low-affinity nerve growth factor receptor
NGF receptor
p75 ICD
CD antigen CD271
Immunogen Recombinant protein of human NGFR
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB IHC IF IP
Host Rabbit
Clonality Monoclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 4804
Gene Symbol NGFR
Molecular Weight 45.183 kDa
Database Links HGNC:7809
OMIM:162010
Reactome:R-HSA-193634
Alternative Names Tumor necrosis factor receptor superfamily member 16 antibody
Gp80-LNGFR antibody
Low affinity neurotrophin receptor p75NTR antibody
Low-affinity nerve growth factor receptor antibody
NGF receptor antibody
p75 ICD antibody
CD antigen CD271 antibody
TNFRSF16 antibody
Function Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake , Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4, Can mediate cell survival as well as cell death of neural cells, Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver,
Post-translational Modifications N- and O-glycosylated
Cellular Localization Membrane
Swiss-Prot Key P08138
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