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Anti-NT-3 antibody

[STJ98718] Download PDF Print Data Sheet
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Product name Anti-NT-3 antibody
Short Description Rabbit polyclonal to NT-3.
Description NT-3 is a protein encoded by the NTF3 gene which is approximately 29,4 kDa. NT-3 is secreted and is involved in apoptotic pathways in synovial fibroblasts, the GPCR pathway, ERK signalling, TGF-beta pathway and nanog in mammalian ESC pluripotency. This protein falls under the neurotrophin family. It controls survival and differentiation of mammalian neurons and is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo. NT-3 is expressed in the brain and peripheral tissues. Mutations in the NTF3 gene result in diabetic neuropathy and pediatric fibrosarcoma. STJ98718 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This polyclonal antibody binds to endogenous NT-3.
Applications ELISA, ICC, IHC
Dilution range IHC-P 1:50-300
ELISA 1:5000-20000
Specificity The antibody detects endogenous NT-3.
Protein Name Neurotrophin-3
NT-3
HDNF
Nerve growth factor 2
NGF-2
Neurotrophic factor
Immunogen Synthetic peptide from human NT-3 protein.
Immunogen Region 180-230 aa
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Isotype IgG
Formulation PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Gene ID 4908
Gene Symbol NTF3
Database Links HGNC:8023
OMIM:162660
Alternative Names
Neurotrophin-3 antibody
NT-3 antibody
HDNF antibody
Nerve growth factor 2 antibody
NGF-2 antibody
Neurotrophic factor antibody
Function Seems to promote the survival of visceral and proprioceptive sensory neurons.
Cellular Localization Secreted.
Tissue Specificity Brain and peripheral tissues.
Swiss-Prot Key P20783_HUMAN
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I am interested in this antibody in 0.3mg size, 1mg/mL. Would it be possible to change the storage buffer to PBS and not include sodium azide?
Question by: Guest on 11 Apr 2018 12:40:00
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Hello, thank you for your query. If you would like to place a custom order, the product should be at least 1 mg. There will be no additional cost for changing the storage buffer. Please contact us at info@stjohnslabs.com for further information.
Answer by: Customer Support on 11 Apr 2018 12:43:00

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