Anti-PDCD10 Antibody

[STJ117595] Download PDF Print Data Sheet

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Product name Anti-PDCD10 Antibody
Short Description Rabbit polyclonal against PDCD10
Description This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Applications WB
Dilution range WB 1:200 - 1:2000
Protein Name Programmed cell death protein 10
Cerebral cavernous malformations 3 protein
TF-1 cell apoptosis-related protein 15
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PDCD10 (NP_009148.2).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 11235
Gene Symbol PDCD10
Molecular Weight 24.702 kDa
Database Links HGNC:8761
OMIM:603285
Alternative Names Programmed cell death protein 10
Cerebral cavernous malformations 3 protein
TF-1 cell apoptosis-related protein 15
Function Promotes cell proliferation, Modulates apoptotic pathways, Increases mitogen-activated protein kinase activity and STK26 activity ,
Cellular Localization Cytoplasm, Golgi apparatus membrane
Tissue Specificity Ubiquitous
Swiss-Prot Key Q9BUL8
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