Anti-COX IV antibody

[STJ96935] Download PDF Print Data Sheet

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Product name Anti-COX IV antibody
Short Description Mouse monoclonal against COX IV
Description COX IV is a protein encoded by the COX4I1 gene which is approximately 19,5 kDa. COX IV is localised to the mitochondrion inner membrane. It is involved in respiratory electron transport, metabolism, gene expression, cardiac muscle contraction, apoptosis and autophagy. It is the terminal enzyme of the mitochondrial respiratory chain and forms a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. COX IV is expressed ubiquitously in human tissue. Mutations in the COX4I1 gene may result in Calvarial hyperostosis. STJ96935 was developed from clone 6C8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous COX IV protein.
Applications WB
Dilution range WB 1:1000-3000
Specificity The antibody detects endogenous COX IV protein.
Protein Name Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Cytochrome c oxidase polypeptide IV
Cytochrome c oxidase subunit IV isoform 1
COX IV-1
Immunogen Recombinant Protein
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Validated Application IF IHC WB
Host Mouse
Clonality Monoclonal
Clone ID 6C8
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Isotype IgG1
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 1327
Gene Symbol COX4I1
Database Links HGNC:2265
OMIM:123864
Alternative Names Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Cytochrome c oxidase polypeptide IV
Cytochrome c oxidase subunit IV isoform 1
COX IV-1
Function This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Cellular Localization Mitochondrion inner membrane.
Tissue Specificity Ubiquitous.
Swiss-Prot Key P13073_HUMAN
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-18
I am interested in this antibody in 0.3mg size, 1mg/mL. Would it be possible to change the storage buffer to PBS and not include sodium azide?
Question by: Guest on 11 Apr 2018 12:40:00
-11
Hello, thank you for your query. If you would like to place a custom order, the product should be at least 1 mg. There will be no additional cost for changing the storage buffer. Please contact us at info@stjohnslabs.com for further information.
Answer by: Customer Support on 11 Apr 2018 12:43:00

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