Trial size DPYSL2 antibodies available in the Antibody Validation Project

Posted by M.Popov on 12th Nov 2020

Trial size DPYSL2 antibodies available in the Antibody Validation Project

Trial size DPYSL2 antibodies available in the Antibody Validation Project

Introduction:

The Dihydropyrimidinase like 2 protein is encoded by the DPYSL2 gene and servers several important roles in the human body. For example, it promotes microtubule assembly and also plays a role in synaptic signaling. The DPYSL2 protein can mainly be found in the cytoplasm of monocytes and myeloid DC. Furthermore, mutations or overexpressions of the gene encoding the DPYSL2 protein can lead to several mental diseases and another use of DPYSL2 is a prognostic marker in unfavourable urothelial cancer. We provide a number of trial sized antibodies, which are suitable for DPYSL2 research purposes, and to help you make the right decision and find the best suited antibody for you, please find the answers to some of the key topics regarding DPYSL2 that we have provided in the links below.

What is DPYSL2?

The DPYSL2 gene encodes a member of the collapsin response mediator protein family, which form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. 

Where is DPYSL2 found?

Inside the cell the DPYSL2 protein can mainly be found in the cytosol and additionally in plasma membrane, and on tissue level, it has higher expression in intermediate monocyte, myeloid DC, classical monocyte, non-classical monocyte and plasmacytoid DC.

What role does DPYSL2 play in disease?

The DPYSL2 gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Furthermore, several other mental diseases including schizophrenia and bipolar disorder have been linked with disorders if this particular gene and its protein.

DPYSL2 antibodies in the Antibody Validation project

St John's Laboratory offers a variety of trial size primary antibodies which target DPYSL2, which are available to try through the Antibody Validation Project. Below we highlight those which have already been reviewed, as well as others which are available to try.

Customer reviewed DPYSL2 antibodies

ModelNameHostClonalityRatingApplication Tested
STJ90974Anti-Phospho-CRMP-2 (T509) antibody RabbitPolyclonal5WB

Other DPYSL2 antibodies available in the Antibody Validation Project

ModelNameHostClonalityRecommended Applications
STJ90673Anti-Phospho-CRMP-2 (S522) antibodyRabbitPolyclonalWB,ELISA
STJ91107Anti-Phospho-CRMP-2 (T514) antibodyRabbitPolyclonalWB,IHC,IF,ELISA
STJ92479Anti-CRMP-2 antibodyRabbitPolyclonalWB,IHC,ELISA
STJ92480Anti-CRMP-2 antibodyRabbitPolyclonalWB,IHC,IF,ELISA
STJ92481Anti-CRMP-2 antibodyRabbitPolyclonalWB,ELISA
ModelNameHostClonalityRecommended Applications
STJ111012Anti-DPYSL2 AntibodyMouseMonoclonalWB
STJ116781Anti-DPYSL2 AntibodyRabbitPolyclonalWB
STJ117919Anti-Phospho-DPYSL2-(T514) AntibodyRabbitPolyclonalWB
STJ500612Anti-DPYSL2 AntibodyRabbitPolyclonalELISA,WB
STJ500613Anti-DPYSL2 Antibody (Biotin)RabbitPolyclonalELISA,WB
STJ500614Anti-DPYSL2 Antibody (FITC)RabbitPolyclonalELISA,WB

How does the Antibody Validation Project work?

In order to help our customers with their choice of antibody with low risk, we offer one of the largest ranges of primary antibodies with trial size options available.

The Antibody Validation Project works like this.
1. Order your trial size antibody online.
2. Explore its suitability.
3. Return your results by posting them on the product page.
4. Receive a sample refund.

Find out more here.