Anti-SPARC antibody




 
Description
Rabbit polyclonal against SPARC
 


Product Information

Model STJ96886
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-p, WB
Immunogen Synthesized peptide derived from human SPARC.
Gene ID 6678
Dilution range WB 1:500-1:2000
IHC-p 1:100-1:300
ELISA 1:20000
Specificity SPARC polyclonal antibody detects endogenous levels of SPARC protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note FOR RESEARCH USE ONLY (RUO).
Protein Name Sparc
Basement-Membrane Protein 40
Bm-40
Osteonectin
On
Secreted Protein Acidic And Rich In Cysteine
Clonality Polyclonal
Conjugation Unconjugated
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration 1 mg/ml
Storage Instruction Store at-20°C, and avoid repeat freeze-thaw cycles.
Database Links HGNC:11219
OMIM:182120
Alternative Names Anti-Sparc antibody
Anti-Basement-Membrane Protein 40 antibody
Anti-Bm-40 antibody
Anti-Osteonectin antibody
Anti-On antibody
Anti-Secreted Protein Acidic And Rich In Cysteine antibody
Anti-SPARC ON antibody
Function Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites.an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
Cellular Localization Secreted
Extracellular Space
Extracellular Matrix
Basement Membrane
In Or Around The Basement Membrane


St John's Laboratory Ltd http://www.stjohnslabs.com/ +44 (0)207 681 2580
  [email protected] +44 (0)208 223 3081