Anti-NGFR Antibody




 
Description
Rabbit monoclonal against NGFR
 


Product Information

Model STJ112916
Host Rabbit
Reactivity Human, Mouse, Rat
Applications IF, IHC, IP, WB
Immunogen Recombinant protein of human NGFR
Gene ID 4804
Dilution range WB 1:10000 - 1:20000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:20 - 1:50
Purification Affinity purification
Note For Research Use Only (RUO).
Protein Name Tumor necrosis factor receptor superfamily member 16
Gp80-LNGFR
Low affinity neurotrophin receptor p75NTR
Low-affinity nerve growth factor receptor
NGF receptor
p75 ICD
CD antigen CD271
Clonality Monoclonal
Conjugation Unconjugated
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Database Links HGNC:7809
OMIM:162010
Reactome:R-HSA-193634
Alternative Names Tumor necrosis factor receptor superfamily member 16
Gp80-LNGFR
Low affinity neurotrophin receptor p75NTR
Low-affinity nerve growth factor receptor
NGF receptor
p75 ICD
CD antigen CD271
Function Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake , Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4, Can mediate cell survival as well as cell death of neural cells, Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver,
Cellular Localization Membrane
Post-translational Modifications N- and O-glycosylated


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  [email protected] +44 (0)208 223 3081