Human S100 Calcium Binding Protein B ELISA kit

Human ELISA Kit to S100B.

Product Information

Model STJ150139
Reactivity Human
Applications ELISA
Gene ID 6285
Dilution range 31.25--2000pg/mL
Protein Name S100B
Storage Instruction Store at 4°C for 6 months.
Database Links HGNC:10500
Alternative Names Protein S100-B, S-100 Protein Beta Chain, S-100 Protein Subunit Beta, S100 Calcium-Binding Protein B
Function Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Cellular Localization Cytoplasm, Nucleus

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