Anti-DCSTAMP Antibody




 
Description
Rabbit polyclonal against DCSTAMP
 


Product Information

Model STJ116837
Host Rabbit
Reactivity Human
Applications WB
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 401-470 of human DCSTAMP (NP_110415.1).
Gene ID 81501
Dilution range WB 1:500 - 1:2000
Purification Affinity purification
Note For Research Use Only (RUO).
Protein Name Dendritic cell-specific transmembrane protein
DC-STAMP
hDC-STAMP
Dendrocyte-expressed seven transmembrane protein
IL-four-induced protein
FIND
Transmembrane 7 superfamily member 4
Clonality Polyclonal
Conjugation Unconjugated
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Database Links HGNC:18549
OMIM:605933
Reactome:R-HSA-8874211
Alternative Names Dendritic cell-specific transmembrane protein
DC-STAMP
hDC-STAMP
Dendrocyte-expressed seven transmembrane protein
IL-four-induced protein
FIND
Transmembrane 7 superfamily member 4
Function Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis, Plays a role in TNFSF11-mediated osteoclastogenesis, Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs), Participates in osteoclast bone resorption, Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors, Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage, Inhibits the development of neutrophilic granulocytes, Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity, Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions
Cellular Localization Cell membrane,
Post-translational Modifications Glycosylated,


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