Anti-ERLIN1 Antibody




 
Description
Rabbit polyclonal against ERLIN1
 


Product Information

Model STJ117043
Host Rabbit
Reactivity Human, Mouse, Rat
Applications WB
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 259-348 of human ERLIN1 (NP_006450.2).
Gene ID 10613
Dilution range WB 1:500 - 1:2000
Purification Affinity purification
Note For Research Use Only (RUO).
Protein Name Erlin-1
Endoplasmic reticulum lipid raft-associated protein 1
Protein KE04
Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
SPFH domain-containing protein 1
Clonality Polyclonal
Conjugation Unconjugated
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Database Links HGNC:16947
OMIM:611604
Reactome:R-HSA-382556
Alternative Names Erlin-1
Endoplasmic reticulum lipid raft-associated protein 1
Protein KE04
Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
SPFH domain-containing protein 1
Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs), Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway, Binds cholesterol and may promote ER retention of the SCAP-SREBF complex ,
Cellular Localization Endoplasmic reticulum membrane,


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