Anti-ERLIN1 antibody

Rabbit polyclonal against ERLIN1

Product Information

Model STJ117043
Host Rabbit
Reactivity Human, Mouse, Rat
Applications WB
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 259-348 of human ERLIN1 (NP_006450. 2).
Gene ID 10613
Dilution range WB 1:500-1:2000
Purification Affinity purification
Protein Name Erlin-1
Endoplasmic Reticulum Lipid Raft-Associated Protein 1
Protein Ke04
Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 1
Spfh Domain-Containing Protein 1
Clonality Polyclonal
Conjugation Unconjugated
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction Store at-20°C and avoid freeze-thaw cycles.
Database Links Reactome: R-HSA-382556
Alternative Names Anti-Erlin-1 antibody
Anti-Endoplasmic Reticulum Lipid Raft-Associated Protein 1 antibody
Anti-Protein Ke04 antibody
Anti-Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 1 antibody
Anti-Spfh Domain-Containing Protein 1 antibody
Anti-ERLIN1 C10orf69 KE04 KEO4 SPFH1 antibody
Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.
Cellular Localization Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Associated With Lipid Raft-Like Domains Of The Endoplasmic Reticulum Membrane

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