Human MMP1 ELISA Kit

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Product name Human MMP1 ELISA Kit
Short Description Human ELISA Kit to MMP1
Description The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of Collagenase I in human serum, plasma and other biological fluids
Applications ELISA
Dilution range 0.156--10ng/mL
Protein Name Interstitial collagenase
Storage Instruction Store at 4°C for 6 months.
Note FOR RESEARCH USE ONLY (RUO) .
Validated Application ELISA
Reactivity Human
Conjugation Unconjugated
Concentration 10ng/mL
Gene ID 4312
Gene Symbol MMP1
Molecular Weight 23.2 kDa
Database Links HGNC:7155
OMIM:120353
Reactome:R-HSA-1442490
Alternative Names Interstitial collagenase
Function Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor, Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16, Does not act on MMP14, Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1, Plays a role in integrin signaling, Mediates erythropoiesis in vitro.
Post-translational Modifications The activity of TIMP1 is dependent on the presence of disulfide bonds
Cellular Localization Secreted, extracellular space, extracellular matrix
Tissue Specificity Serum, Plasma, Biological Fluids
Swiss-Prot Key P03956
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