Human B2M ELISA Kit

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Product name Human B2M ELISA Kit
Short Description Human ELISA Kit to B2M
Description The kit is a competitive enzyme immunoassay for in vitro quantitative measurement of BMG/beta2-MG in human serum, plasma and other biological fluids
Applications ELISA
Dilution range 31.25--2000ng/mL
Protein Name Beta-2-microglobulin
Storage Instruction Store at 4°C for 6 months.
Note FOR RESEARCH USE ONLY (RUO) .
Validated Application ELISA
Reactivity Human
Conjugation Unconjugated
Concentration 2000ng/mL
Gene ID 567
Gene Symbol B2M
Molecular Weight 13.7 kDa
Database Links HGNC:914
OMIM:105200
Reactome:R-HSA-1236974
Alternative Names Beta-2-microglobulin
Function Component of the class I major histocompatibility complex (MHC) , Involved in the presentation of peptide antigens to the immune system, Exogenously applied M, tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change) , probably leading to defects in class I antigen presentation.
Post-translational Modifications Glycation of Ile-21 is observed in long-term hemodialysis patients
Cellular Localization Secreted
Tissue Specificity Serum, Plasma, Biological Fluids
Swiss-Prot Key P61769
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