Human BMP10 ELISA Kit

[STJ150132] Download PDF Print Data Sheet
Product name Human BMP10 ELISA Kit
Short Description Human ELISA Kit to BMP10
Description The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of BMP-1 in human serum, plasma and other biological fluids
Applications ELISA
Dilution range 0.156--10ng/mL
Protein Name Bone morphogenetic protein 10
Storage Instruction Store at 4°C for 6 months.
Note For Research Use Only (RUO).
Validated Application ELISA
Conjugation Unconjugated
Concentration 10ng/mL
Gene ID 27302
Gene Symbol BMP10
Molecular Weight 48 kDa
Database Links HGNC:20869
Alternative Names Bone morphogenetic protein 10
Function Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5, Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors, Inhibits endothelial cell migration and growth, May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Cellular Localization Secreted
Tissue Specificity Serum, Plasma, Biological Fluids
Swiss-Prot Key O95393
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