Human Bone Morphogenetic Protein 1 ELISA kit

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Product name Human Bone Morphogenetic Protein 1 ELISA kit
Short Description Human ELISA Kit to BMP-1.
Description The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of BMP-1 in Human serum, plasma and other biological fluids.
Applications ELISA
Dilution range 0.156--10ng/mL
Protein Name BMP-1
Storage Instruction Store at 4°C for 6 months.
Note FOR RESEARCH USE ONLY (RUO) .
Validated Application ELISA
Reactivity Human
Gene ID 649
Gene Symbol BMP1
Molecular Weight 48 kDa
Database Links HGNC:20869
OMIM:608748
Reactome:R-HSA-201451
Alternative Names Bone Morphogenetic Protein 1, Bmp-1, Mammalian Tolloid Protein, Mtld, Procollagen C-Proteinase, Pcp
Function Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD) . Responsible for the proteolytic activation of lysyl oxidase LOX.
Post-translational Modifications Proteolytically activated in the trans-Golgi network by furin-like/paired basic proprotein convertases, cleavage is not required for secretion.
Cellular Localization Golgi Apparatus, Trans-Golgi Network, Secreted, Extracellular Space, Extracellular Matrix, Note=Co-Localizes With Postn In The Golgi
Tissue Specificity Serum, Plasma, Biological Fluids
Swiss-Prot Key BMP1_HUMAN
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