Human Carcinoembryonic Antigen ELISA kit

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Product name Human Carcinoembryonic Antigen ELISA kit
Short Description Human ELISA Kit to CEA.
Description The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of CEA in Human serum, plasma and other biological fluids.
Applications ELISA
Dilution range 0.625--40ng/mL
Protein Name CEA
Storage Instruction Store at 4°C for 6 months.
Validated Application ELISA
Reactivity Human
Gene ID 1048
Gene Symbol CEACAM5
Molecular Weight 32.4 kDa
Database Links HGNC:28834
Alternative Names Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5, Carcinoembryonic Antigen, Cea, Meconium Antigen 100, Cd Antigen Cd66e
Function Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.; (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
Post-translational Modifications Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
Cellular Localization Cell Membrane, Lipid-Anchor, Gpi-Anchor, Apical Cell Membrane, Cell Surface, Note=Localized To The Apical Glycocalyx Surface
Tissue Specificity Serum, Plasma, Biological Fluids
Swiss-Prot Key CEAM5_HUMAN
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