Human CXCL8 ELISA Kit

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Product name Human CXCL8 ELISA Kit
Short Description Human ELISA Kit to CXCL8
Description The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of IL-8 in human serum, plasma and other biological fluids
Applications ELISA
Dilution range 31.25--2000pg/mL
Protein Name Interleukin-8
IL-8
C-X-C motif chemokine 8
Chemokine
C-X-C motif
ligand 8
Emoctakin
Granulocyte chemotactic protein 1
GCP-1
Monocyte-derived neutrophil chemotactic factor
MDNCF
Monocyte-derived neutrophil-activa
Storage Instruction Store at 4°C for 6 months.
Note FOR RESEARCH USE ONLY (RUO) .
Validated Application ELISA
Reactivity Human
Conjugation Unconjugated
Concentration 2000pg/mL
Gene ID 3576
Gene Symbol CXCL8
Molecular Weight 11.1 kDa
Database Links HGNC:6025
OMIM:146930
Reactome:R-HSA-2559582
Alternative Names Interleukin-8
IL-8
C-X-C motif chemokine 8
Chemokine
C-X-C motif
ligand 8
Emoctakin
Granulocyte chemotactic protein 1
GCP-1
Monocyte-derived neutrophil chemotactic factor
MDNCF
Monocyte-derived neutrophil-activa
Function IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes, It is also involved in neutrophil activation, It is released from several cell types in response to an inflammatory stimulus, IL-8 (6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8 (5-77) has increased activity on neutrophil activation and IL-8 (7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8 (1-77) , respectively.
Post-translational Modifications Several N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells, In general, IL-8 (1-77) is referred to as interleukin-8, IL-8 (6-77) is the most promiment form
Cellular Localization Secreted
Tissue Specificity Serum, Plasma, Biological Fluids
Swiss-Prot Key P10145
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