Human Monocyte Chemotactic Protein 1 ELISA kit

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Product name Human Monocyte Chemotactic Protein 1 ELISA kit
Short Description Human ELISA Kit to MCP-1.
Description The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of MCP-1 in Human serum, plasma and other biological fluids.
Applications ELISA
Dilution range 15.625--1000pg/mL
Protein Name MCP-1
Storage Instruction Store at 4°C for 6 months.
Note FOR RESEARCH USE ONLY (RUO) .
Validated Application ELISA
Reactivity Human
Gene ID 6347
Gene Symbol CCL2
Molecular Weight 11 kDa
Database Links HGNC:10618
OMIM:158105
Reactome:R-HSA-380994
Alternative Names C-C Motif Chemokine 2, Hc11, Monocyte Chemoattractant Protein 1, Monocyte Chemotactic And Activating Factor, Mcaf, Monocyte Chemotactic Protein 1, Mcp-1, Monocyte Secretory Protein Je, Small-Inducible Cytokine A2
Function Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Post-translational Modifications Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant.; N-Glycosylated.
Cellular Localization Secreted
Tissue Specificity Serum, Plasma, Biological Fluids
Swiss-Prot Key CCL2_HUMAN
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