Human Monocyte Chemotactic Protein 4 ELISA kit

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Product name Human Monocyte Chemotactic Protein 4 ELISA kit
Short Description Human ELISA Kit to MCP-4/CCL13.
Description The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of MCP-4/CCL13 in Human serum, plasma and other biological fluids.
Applications ELISA
Dilution range 15.625--1000pg/mL
Protein Name MCP-4/CCL13
Storage Instruction Store at 4°C for 6 months.
Note FOR RESEARCH USE ONLY (RUO) .
Validated Application ELISA
Reactivity Human
Gene ID 6357
Gene Symbol CCL13
Molecular Weight 11 kDa
Database Links HGNC:10611
OMIM:601391
Reactome:R-HSA-380108
Alternative Names C-C Motif Chemokine 13, Ck-Beta-10, Monocyte Chemoattractant Protein 4, Monocyte Chemotactic Protein 4, Mcp-4, Ncc-1, Small-Inducible Cytokine A13 [Cleaved Into-C-C Motif Chemokine 13-Long Chain-C-C Motif Chemokine 13-Medium Chain-C-C Motif Chemokine 13-Short Chain]
Function Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
Post-translational Modifications One major form (form long) , and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain.
Cellular Localization Secreted
Tissue Specificity Serum, Plasma, Biological Fluids
Swiss-Prot Key CCL13_HUMAN
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