Anti-A Cyclase V/VI antibody (931-980 aa) (STJ91397)

SKU:
STJ91397
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Adenylate cyclase type 5 and Adenylate cyclase type 6 (931-980 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/IF/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ADCY5
ADCY6
Gene ID:111
112
Uniprot ID:ADCY5_HUMAN
ADCY6_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human ADCY5/6 at the amino acid range 931-980
Immunogen Region:931-980 aa
Specificity:A Cyclase V/VI Polyclonal Antibody detects endogenous levels of A Cyclase V/VI protein.
Post Translational Modifications Phosphorylated by RAF1.
Function Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion.
Protein Name Adenylate Cyclase Type 5
Atp Pyrophosphate-Lyase 5
Adenylate Cyclase Type V
Adenylyl Cyclase 5
Ac5
Database Links Reactome: R-HSA-163359
Reactome: R-HSA-163615
Reactome: R-HSA-164378
Reactome: R-HSA-170660
Reactome: R-HSA-170670
Reactome: R-HSA-381676
Reactome: R-HSA-400042
Reactome: R-HSA-418555
Reactome: R-HSA-418594
Reactome: R-HSA-418597
Reactome: R-HSA-432040
Reactome: R-HSA-5610787
Reactome: R-HSA-9660821
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Cilium
Alternative Antibody Names Anti-Adenylate Cyclase Type 5 antibody
Anti-Atp Pyrophosphate-Lyase 5 antibody
Anti-Adenylate Cyclase Type V antibody
Anti-Adenylyl Cyclase 5 antibody
Anti-Ac5 antibody
Anti-ADCY5 antibody

Information sourced from Uniprot.org