| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S1MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACTN3 |
| Gene ID: | 89 |
| Uniprot ID: | ACTN3_HUMAN |
| Immunogen Region: | 700-800 |
| Immunogen Sequence: | DRLEGDHQLLQESLVFDNKH TVYSMEHIRVGWEQLLTSIA RTINEVENQVLTRDAKGLSQ EQLNEFRASFNHFDRKQNGM MEPDDFRACLISMGYDLGEV E |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 700-800 of human ACTN3 (Q08043). |
| Tissue Specificity | Expression restricted to fast (type 2) skeletal muscle fibers (at protein level). |
| Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
| Protein Name | Alpha-Actinin-3Alpha-Actinin Skeletal Muscle Isoform 3F-Actin Cross-Linking Protein |
| Database Links | Reactome: R-HSA-373753Reactome: R-HSA-390522 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Alpha-Actinin-3 antibodyAnti-Alpha-Actinin Skeletal Muscle Isoform 3 antibodyAnti-F-Actin Cross-Linking Protein antibodyAnti-ACTN3 antibody |
Information sourced from Uniprot.org
![Immunohistochemistry analysis of STAT3 in paraffin-embedded human brain tissue using [KO Validated] STAT3 Rabbit monoclonal antibody (STJ11101701) at a dilution of 1:200 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/90616/360464/STJ11101701_1__07605.1713125126.jpg?c=1 "Immunohistochemistry analysis of STAT3 in paraffin-embedded human brain tissue using [KO Validated] STAT3 Rabbit monoclonal antibody (STJ11101701) at a dilution of 1:200 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.")
