Anti-ACTN3 antibody (700-800) [S1MR] (STJ11103061)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal ACTN3 (700-800) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S1MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACTN3 |
| Gene ID | 89 |
| Uniprot ID | ACTN3_HUMAN |
| Immunogen Region | 700-800 |
| Immunogen Sequence | DRLEGDHQLLQESLVFDNKH TVYSMEHIRVGWEQLLTSIA RTINEVENQVLTRDAKGLSQ EQLNEFRASFNHFDRKQNGM MEPDDFRACLISMGYDLGEV E |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 700-800 of human ACTN3 (Q08043). |
Additional Info
| Tissue Specificity | Expression restricted to fast (type 2) skeletal muscle fibers (at protein level). |
| Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
| Protein Name | Alpha-Actinin-3Alpha-Actinin Skeletal Muscle Isoform 3F-Actin Cross-Linking Protein |
| Database Links | Reactome: R-HSA-373753Reactome: R-HSA-390522 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Alpha-Actinin-3 antibodyAnti-Alpha-Actinin Skeletal Muscle Isoform 3 antibodyAnti-F-Actin Cross-Linking Protein antibodyAnti-ACTN3 antibody |
Information sourced from Uniprot.org