| Short Description : | Rabbit polyclonal anti-A-kinase anchor protein 1, mitochondrial (281-330 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AKAP1 |
| Gene ID: | 8165 |
| Uniprot ID: | AKAP1_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human AKAP1 at the amino acid range 281-330 |
| Immunogen Region: | 281-330 aa |
| Specificity: | AKAP 149 Polyclonal Antibody detects endogenous levels of AKAP 149 protein. |
| Function | Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane. Involved in mitochondrial-mediated antiviral innate immunity. Promotes translocation of NDUFS1 into mitochondria to regulate mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) activity. |
| Protein Name | A-Kinase Anchor Protein 1 - MitochondrialA-Kinase Anchor Protein 149 KdaAkap 149Dual Specificity A-Kinase-Anchoring Protein 1D-Akap-1Protein Kinase A-Anchoring Protein 1Prka1Spermatid A-Kinase Anchor Protein 84S-Akap84 |
| Database Links | Reactome: R-HSA-8949215Reactome: R-HSA-983231 |
| Cellular Localisation | Mitochondrion Outer MembraneMitochondrion |
| Alternative Antibody Names | Anti-A-Kinase Anchor Protein 1 - Mitochondrial antibodyAnti-A-Kinase Anchor Protein 149 Kda antibodyAnti-Akap 149 antibodyAnti-Dual Specificity A-Kinase-Anchoring Protein 1 antibodyAnti-D-Akap-1 antibodyAnti-Protein Kinase A-Anchoring Protein 1 antibodyAnti-Prka1 antibodyAnti-Spermatid A-Kinase Anchor Protein 84 antibodyAnti-S-Akap84 antibodyAnti-AKAP1 antibodyAnti-AKAP149 antibodyAnti-PRKA1 antibody |
Information sourced from Uniprot.org
