Anti-AP1M2 antibody (164-423) (STJ110629)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AP1M2 (164-423) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AP1M2 |
| Gene ID | 10053 |
| Uniprot ID | AP1M2_HUMAN |
| Immunogen Region | 164-423 |
| Immunogen Sequence | IKYKKNEVFIDVIESVNLLV NANGSVLLSEIVGTIKLKVF LSGMPELRLGLNDRVLFELT GRSKNKSVELEDVKFHQCVR LSRFDNDRTISFIPPDGDFE LMSYRLSTQVKPLIWIESVI EKFSHSRVEIMVKAKGQFKK QSVANGVEISVPVPSDADSP RFKTSVGSAKYVPERNVVIW SIKSFPGGKEYLMRAHFGLP SVEKEEVEGRPPIGVKFEIP YFTVSGIQVRYMKIIEKSG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 164-423 of human AP1M2 (NP_005489.2). |
Additional Info
| Post Translational Modifications | Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals. |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| Protein Name | Ap-1 Complex Subunit Mu-2Ap-Mu Chain Family Member Mu1bAdaptor Protein Complex Ap-1 Subunit Mu-2Adaptor-Related Protein Complex 1 Subunit Mu-2Clathrin Assembly Protein Complex 1 Mu-2 Medium Chain 2Golgi Adaptor Ha1/Ap1 Adaptin Mu-2 SubunitMu-Adaptin 2Mu1b-Adaptin |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Antibody Names | Anti-Ap-1 Complex Subunit Mu-2 antibodyAnti-Ap-Mu Chain Family Member Mu1b antibodyAnti-Adaptor Protein Complex Ap-1 Subunit Mu-2 antibodyAnti-Adaptor-Related Protein Complex 1 Subunit Mu-2 antibodyAnti-Clathrin Assembly Protein Complex 1 Mu-2 Medium Chain 2 antibodyAnti-Golgi Adaptor Ha1/Ap1 Adaptin Mu-2 Subunit antibodyAnti-Mu-Adaptin 2 antibodyAnti-Mu1b-Adaptin antibodyAnti-AP1M2 antibody |
Information sourced from Uniprot.org