Anti-AP1M2 antibody (164-423) (STJ110629)

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STJ110629
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Short Description :Rabbit polyclonal AP1M2 (164-423) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:AP1M2
Gene ID:10053
Uniprot ID:AP1M2_HUMAN
Immunogen Region:164-423
Immunogen Sequence:IKYKKNEVFIDVIESVNLLV NANGSVLLSEIVGTIKLKVF LSGMPELRLGLNDRVLFELT GRSKNKSVELEDVKFHQCVR LSRFDNDRTISFIPPDGDFE LMSYRLSTQVKPLIWIESVI EKFSHSRVEIMVKAKGQFKK QSVANGVEISVPVPSDADSP RFKTSVGSAKYVPERNVVIW SIKSFPGGKEYLMRAHFGLP SVEKEEVEGRPPIGVKFEIP YFTVSGIQVRYMKIIEKSG
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 164-423 of human AP1M2 (NP_005489.2).
Post Translational Modifications Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals.
Function Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Protein Name Ap-1 Complex Subunit Mu-2
Ap-Mu Chain Family Member Mu1b
Adaptor Protein Complex Ap-1 Subunit Mu-2
Adaptor-Related Protein Complex 1 Subunit Mu-2
Clathrin Assembly Protein Complex 1 Mu-2 Medium Chain 2
Golgi Adaptor Ha1/Ap1 Adaptin Mu-2 Subunit
Mu-Adaptin 2
Mu1b-Adaptin
Database Links Reactome: R-HSA-164940
Reactome: R-HSA-2132295
Reactome: R-HSA-432720
Reactome: R-HSA-432722
Cellular Localisation Golgi Apparatus
Cytoplasmic Vesicle
Clathrin-Coated Vesicle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Component Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex
Alternative Antibody Names Anti-Ap-1 Complex Subunit Mu-2 antibody
Anti-Ap-Mu Chain Family Member Mu1b antibody
Anti-Adaptor Protein Complex Ap-1 Subunit Mu-2 antibody
Anti-Adaptor-Related Protein Complex 1 Subunit Mu-2 antibody
Anti-Clathrin Assembly Protein Complex 1 Mu-2 Medium Chain 2 antibody
Anti-Golgi Adaptor Ha1/Ap1 Adaptin Mu-2 Subunit antibody
Anti-Mu-Adaptin 2 antibody
Anti-Mu1b-Adaptin antibody
Anti-AP1M2 antibody

Information sourced from Uniprot.org