Anti-ARHGAP4 antibody (900 aa) (STJ11100294)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11100294
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General Information

Short DescriptionRabbit polyclonal ARHGAP4 (900 aa) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/IF/ICC/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
IHC-P:1:50-1:200
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolARHGAP4
Gene ID393
Uniprot IDRHG04_HUMAN
Immunogen Region900 aa
Immunogen SequenceSPEQHVEVDKAVAQNMDSVF KELLGKTSVRQGLGPASTTS PSPGPRSPKAPPSSRLGRNK GFSRGPGAPASPSASHPQGL DTTPKPH
SpecificityA synthetic peptide corresponding to a sequence within amino acids 900 to the C-terminus of human ARHGAP4 (NP_001158213.1).

Additional Info

Tissue Specificity Predominantly in hematopoietic cells (spleen, thymus and leukocytes).low levels in placenta, lung and various fetal tissues.
Function Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells.
Protein Name Rho Gtpase-Activating Protein 4
Rho-Gap Hematopoietic Protein C1
Rho-Type Gtpase-Activating Protein 4
P115
Database Links Reactome: R-HSA-8980692
Reactome: R-HSA-9013148
Reactome: R-HSA-9013149
Cellular Localisation Cytoplasm
Just Below The Plasma Membrane
Alternative Antibody Names Anti-Rho Gtpase-Activating Protein 4 antibody
Anti-Rho-Gap Hematopoietic Protein C1 antibody
Anti-Rho-Type Gtpase-Activating Protein 4 antibody
Anti-P115 antibody
Anti-ARHGAP4 antibody
Anti-KIAA0131 antibody
Anti-RGC1 antibody
Anti-RHOGAP4 antibody

Information sourced from Uniprot.org

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