| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Acid-sensing ion channel 2 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ASIC2 |
| Gene ID: | 40 |
| Uniprot ID: | ASIC2_HUMAN |
| Specificity: | This antibody detects endogenous levels of ASIC2 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human ASIC2 |
| Function | Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. |
| Protein Name | Acid-Sensing Ion Channel 2 Asic2 Amiloride-Sensitive Brain Sodium Channel Amiloride-Sensitive Cation Channel 1 - Neuronal Amiloride-Sensitive Cation Channel Neuronal 1 Brain Sodium Channel 1 Bnc1 Bnac1 Mammalian Degenerin Homolog Mdeg |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Localized At The Plasma Membrane Of Neurons In The Soma And Punctated Peripheral Processes |
| Alternative Antibody Names | Anti-Acid-Sensing Ion Channel 2 antibody Anti-Asic2 antibody Anti-Amiloride-Sensitive Brain Sodium Channel antibody Anti-Amiloride-Sensitive Cation Channel 1 - Neuronal antibody Anti-Amiloride-Sensitive Cation Channel Neuronal 1 antibody Anti-Brain Sodium Channel 1 antibody Anti-Bnc1 antibody Anti-Bnac1 antibody Anti-Mammalian Degenerin Homolog antibody Anti-Mdeg antibody Anti-ASIC2 antibody Anti-ACCN antibody Anti-ACCN1 antibody Anti-BNAC1 antibody Anti-MDEG antibody |
Information sourced from Uniprot.org