| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATP1B2 |
| Gene ID: | 482 |
| Uniprot ID: | AT1B2_HUMAN |
| Immunogen Region: | 68-290 |
| Immunogen Sequence: | DHTPKYQDRLATPGLMIRPK TENLDVIVNVSDTESWDQHV QKLNKFLEPYNDSIQAQKND VCRPGRYYEQPDNGVLNYPK RACQFNRTQLGNCSGIGDST HYGYSTGQPCVFIKMNRVIN FYAGANQSMNVTCAGKRDED AENLGNFVMFPANGNIDLMY FPYYGKKFHVNYTQPLVAVK FLNVTPNVEVNVECRINAAN IATDDERDKFAGRVAFKLRI NKT |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 68-290 of human ATP1B2 (NP_001669.3). |
| Function | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth. |
| Protein Name | Sodium/Potassium-Transporting Atpase Subunit Beta-2Adhesion Molecule In GliaAmogSodium/Potassium-Dependent Atpase Subunit Beta-2 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-5578775Reactome: R-HSA-936837Reactome: R-HSA-9679191 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Sodium/Potassium-Transporting Atpase Subunit Beta-2 antibodyAnti-Adhesion Molecule In Glia antibodyAnti-Amog antibodyAnti-Sodium/Potassium-Dependent Atpase Subunit Beta-2 antibodyAnti-ATP1B2 antibody |
Information sourced from Uniprot.org
