Anti-BYSL antibody (120-280) (STJ113897)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal BYSL (120-280) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BYSL |
| Gene ID | 705 |
| Uniprot ID | BYST_HUMAN |
| Immunogen Region | 120-280 |
| Immunogen Sequence | HAEVVVDPEDERAIEMFMNK NPPARRTLADIIMEKLTEKQ TEVETVMSEVSGFPMPQLDP RVLEVYRGVREVLSKYRSGK LPKAFKIIPALSNWEQILYV TEPEAWTAAAMYQATRIFAS NLKERMAQRFYNLVLLPRVR DDVAEYKRLNFHLYMALKKA L |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human BYSL (NP_004044.3). |
Additional Info
| Tissue Specificity | Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. |
| Function | Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos. |
| Protein Name | Bystin |
| Database Links | Reactome: R-HSA-6791226 |
| Cellular Localisation | CytoplasmNucleusNucleolusAssociated With 40s Ribosomal Subunits |
| Alternative Antibody Names | Anti-Bystin antibodyAnti-BYSL antibodyAnti-ENP1 antibody |
Information sourced from Uniprot.org