Anti-CALB2 antibody (1-271) (STJ111849)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CALB2 (1-271) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CALB2 |
| Gene ID | 794 |
| Uniprot ID | CALB2_HUMAN |
| Immunogen Region | 1-271 |
| Immunogen Sequence | MAGPQQQPPYLHLAELTASQ FLEIWKHFDADGNGYIEGKE LENFFQELEKARKGSGMMSK SDNFGEKMKEFMQKYDKNSD GKIEMAELAQILPTEENFLL CFRQHVGSSAEFMEAWRKYD TDRSGYIEANELKGFLSDLL KKANRPYDEPKLQEYTQTIL RMFDLNGDGKLGLSEMSRLL PVQENFLLKFQGMKLTSEEF NAIFTFYDKDRSGYIDEHEL DALLKDLYEKNKKEMNIQQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-271 of human Calretinin (NP_001731.2). |
Additional Info
| Tissue Specificity | Brain. |
| Function | Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways. Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory. During embryonic development, it facilitates neuronal differentiation and maturation. |
| Protein Name | CalretininCr29 Kda Calbindin |
| Database Links | |
| Cellular Localisation | SynapseCell ProjectionDendriteLocated In DendriolesSmall Dendrites That Makes Up A Brush Structure Found As The Terminal Specialization Of A Dendrite Of A Unipolar Brush Cell |
| Alternative Antibody Names | Anti-Calretinin antibodyAnti-Cr antibodyAnti-29 Kda Calbindin antibodyAnti-CALB2 antibodyAnti-CAB29 antibody |
Information sourced from Uniprot.org