| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CALCRL (392-461) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CALCRL |
| Gene ID: |
10203 |
| Uniprot ID: |
CALRL_HUMAN |
| Immunogen Region: |
392-461 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 392-461 of human CALCRL (NP_005786.1). |
| Immunogen Sequence: |
QAILRRNWNQYKIQFGNSFS NSEALRSASYTVSTISDGPG YSHDCPSEHLNGKSIHDIEN VLLKPENLYN |
| Tissue Specificity | Predominantly expressed in the lung and heart. |
| Function | Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| Protein Name | Calcitonin Gene-Related Peptide Type 1 ReceptorCgrp Type 1 ReceptorCalcitonin Receptor-Like Receptor |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Calcitonin Gene-Related Peptide Type 1 Receptor antibodyAnti-Cgrp Type 1 Receptor antibodyAnti-Calcitonin Receptor-Like Receptor antibodyAnti-CALCRL antibodyAnti-CGRPR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
