Anti-CD103/Itgae antibody [M290] (STJA0001550)

SKU:
STJA0001550

Current Stock:
Host: Rat
Applications: FC/IHC/Block
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rat monoclonal antibody anti-Integrin alpha-E is suitable for use in Flow Cytometry, Immunohistochemistry and Universal research applications.
Clonality: Monoclonal
Clone ID: M290
Conjugation: Unconjugated
Isotype: IgG2ak
Formulation: 0.2 µm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as determined by LAL gel clotting assay.
Concentration: 0.5 mg/mL
Storage Instruction: Store at 2-8°C. Do not freeze this product.
Gene Symbol: Itgae
Gene ID: 16407
Uniprot ID: ITAE_MOUSE
Function Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall.
Protein Name Integrin Alpha-E
Integrin Alpha M290
Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain
Database Links Reactome: R-MMU-216083
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Integrin Alpha-E antibody
Anti-Integrin Alpha M290 antibody
Anti-Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain antibody
Anti-Itgae antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance