Anti-CD34 antibody

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Product name Anti-CD34 antibody
Description Rabbit polyclonal to CD34.
Applications ELISA, WB
Dilution range WB 1:500-1:2000
ELISA 1:10000
Specificity CD34 Polyclonal Antibody detects endogenous levels of CD34 protein.
Protein Name Hematopoietic progenitor cell antigen CD34
CD antigen CD34
Immunogen Synthesized peptide derived from human CD34.
Immunogen Region Internal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Validated Application IHC WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 947
Gene Symbol CD34
Molecular Weight 36 kDa
Database Links HGNC:1662
OMIM:142230
Alternative Names Hematopoietic progenitor cell antigen CD34 antibody
CD antigen CD34 antibody
Function Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
Post-translational Modifications Highly glycosylated.; Phosphorylated on serine residues by PKC.
Cellular Localization Membrane. Single-pass type I membrane protein.
Tissue Specificity Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
Swiss-Prot Key P28906_HUMAN
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