| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CD3EAP (Internal) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000. WB: Preliminary experiments in nuclear lysates of cell lines HeLa, Jurkat and A431 gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate a |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | POLR1G |
| Gene ID: | 10849 |
| Uniprot ID: | RPA34_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_036231.1 |
| Immunogen Sequence: | PEDKTVKQEQINTEP |
| Function | Component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Involved in UBTF-activated transcription, presumably at a step following PIC formation. Isoform 2: Has been described as a component of preformed T-cell receptor (TCR) complex. |
| Protein Name | Dna-Directed Rna Polymerase I Subunit Rpa34 A34.5 Antisense To Ercc-1 Protein Ase-1 Cd3-Epsilon-Associated Protein Cd3e-Associated Protein Dna-Directed Rna Polymerase I Subunit G Rna Polymerase I-Associated Factor Paf49 |
| Database Links | Reactome: R-HSA-427413 Reactome: R-HSA-5250924 Reactome: R-HSA-73762 Reactome: R-HSA-73772 Reactome: R-HSA-73863 |
| Cellular Localisation | Nucleus Nucleolus Chromosome Found At The Fibrillar Centers Of The Nucleolus In Interphase And During Cell Division It Is Localized To The Nucleolus Organizer Regions Of The Chromosomes |
| Alternative Antibody Names | Anti-Dna-Directed Rna Polymerase I Subunit Rpa34 antibody Anti-A34.5 antibody Anti-Antisense To Ercc-1 Protein antibody Anti-Ase-1 antibody Anti-Cd3-Epsilon-Associated Protein antibody Anti-Cd3e-Associated Protein antibody Anti-Dna-Directed Rna Polymerase I Subunit G antibody Anti-Rna Polymerase I-Associated Factor Paf49 antibody Anti-POLR1G antibody Anti-ASE1 antibody Anti-CAST antibody Anti-CD3EAP antibody Anti-PAF49 antibody |
Information sourced from Uniprot.org