Anti-CDNF antibody (STJA0002819)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human CDNF protein produced using CHO-based proprietary suspension cell line. Purified from cell culture supernatant. . Human CDNF
General Information
| Short Description | Rabbit polyclonal anti-CDNF for use in ELISA, WB, IF and IHC-P in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/IF/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | CDNF-affinity purification |
| Dilution Range | ELISA 0.1 to 0.2 µg/ml; WB 0.1 to 0.2 µg/ml; IF 0.3 to 2 µg/mlIHC-P (on formalin-fixed, paraffin-embedded tissues, antigen retrieval)-5 to 10 µg/ml;Monoclonal antibody working dilution has to be established practically for each particular antigen and |
| Formulation | 50% saturated ammonium sulphate in PBS pH 7.4 |
| Storage Instruction | Store at +4°C upon receipt. As product is (NH4) 2SO4 precipitate, mix well by pipetting or vortexing prior use |
Target Information
| Gene Symbol | CDNF |
| Gene ID | 441549 |
| Uniprot ID | CDNF_HUMAN |
| Immunogen | Recombinant human CDNF protein produced using CHO-based proprietary suspension cell line. Purified from cell culture supernatant. . Human CDNF |
| Specificity | Human, mouse; others not tested |
Additional Info
| Tissue Specificity | Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. |
| Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. |
| Protein Name | Cerebral Dopamine Neurotrophic FactorArmet-Like Protein 1Conserved Dopamine Neurotrophic Factor |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cerebral Dopamine Neurotrophic Factor antibodyAnti-Armet-Like Protein 1 antibodyAnti-Conserved Dopamine Neurotrophic Factor antibodyAnti-CDNF antibodyAnti-ARMETL1 antibody |
Information sourced from Uniprot.org