| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CNN3 |
| Gene ID: | 1266 |
| Uniprot ID: | CNN3_HUMAN |
| Immunogen Region: | 220-329 |
| Immunogen Sequence: | LAPGTRRDIYDQKLTLQPVD NSTISLQMGTNKVASQKGMS VYGLGRQVYDPKYCAAPTEP VIHNGSQGTGTNGSEISDSD YQAEYPDEYHGEYQDDYPRD YQYSDQGIDY |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-329 of human CNN3 (NP_001830.1). |
| Tissue Specificity | Expressed in both non-smooth muscle tissues as well as smooth muscle tissues. |
| Function | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
| Protein Name | Calponin-3Calponin - Acidic Isoform |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Calponin-3 antibodyAnti-Calponin - Acidic Isoform antibodyAnti-CNN3 antibody |
Information sourced from Uniprot.org
