| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | COL10A1 |
| Gene ID: | 1300 |
| Uniprot ID: | COAA1_HUMAN |
| Immunogen Region: | 521-680 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 521-680 of human Collagen X/Collagen X/COL10A1 (NP_000484.2). |
| Immunogen Sequence: | MPEGFIKAGQRPSLSGTPLV SANQGVTGMPVSAFTVILSK AYPAIGTPIPFDKILYNRQQ HYDPRTGIFTCQIPGIYYFS YHVHVKGTHVWVGLYKNGTP VMYTYDEYTKGYLDQASGSA IIDLTENDQVWLQLPNAESN GLYSSEYVHSSFSGFLVAPM |
| Post Translational Modifications | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. |
| Function | Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage. |
| Protein Name | Collagen Alpha-1(X Chain |
| Database Links | Reactome: R-HSA-1442490 Reactome: R-HSA-1650814 Reactome: R-HSA-2022090 Reactome: R-HSA-216083 Reactome: R-HSA-3000171 Reactome: R-HSA-8948216 |
| Cellular Localisation | Secreted Extracellular Space Extracellular Matrix |
| Alternative Antibody Names | Anti-Collagen Alpha-1(X Chain antibody Anti-COL10A1 antibody |
Information sourced from Uniprot.org