Anti-Cyclin A antibody (221-270 aa) (STJ92532)

SKU:
STJ92532
£49.00 - £261.00
Processing The item has been added

Short Description :Rabbit polyclonal anti-Cyclin-A1 and Cyclin-A2 (221-270 aa) for use in WB, IHC, IF and ELISA in Human, Mouse, Rat and Monkey samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/IF/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat/Monkey
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CCNA2
CCNA1
Gene ID:890
8900
Uniprot ID:CCNA2_HUMAN
CCNA1_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human Cyclin A at the amino acid range 221-270
Immunogen Region:221-270 aa
Specificity:Cyclin A Polyclonal Antibody detects endogenous levels of Cyclin A protein.
Post Translational Modifications Polyubiquitinated via 'Lys-11'-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.
Function May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
Protein Name Cyclin-A1
Database Links Reactome: R-HSA-1538133
Reactome: R-HSA-170145
Reactome: R-HSA-171319
Reactome: R-HSA-174184
Reactome: R-HSA-176408
Reactome: R-HSA-187577
Reactome: R-HSA-2559582
Reactome: R-HSA-2559586
Reactome: R-HSA-5689880
Reactome: R-HSA-5693607
Reactome: R-HSA-6804116
Reactome: R-HSA-6804756
Reactome: R-HSA-6804757
Reactome: R-HSA-68911
Reactome: R-HSA-68949
Reactome: R-HSA-69017
Reactome: R-HSA-69205
Reactome: R-HSA-69273
Reactome: R-HSA-69563
Reactome: R-HSA-69656
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Cyclin-A1 antibody
Anti-CCNA1 antibody

Information sourced from Uniprot.org