Anti-DCTN3 antibody (Internal) (STJ72400)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-DCTN3 (Internal) is suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry research applications. |
| Applications | Pep-ELISA/WB/IHC/FC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 20kDa band observed in Human Liver lysates, and approx. 18kDa in Rat Kidney lysates and in preliminary testing of Mouse Kidney lysate (calculated MW of 19.5kDa according to Huma |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | DCTN3 |
| Gene ID | 11258 |
| Uniprot ID | DCTN3_HUMAN |
| Accession Number | NP_009165.1; NP_077324.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | QVALGNISSKRE |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_009165.1; NP_077324.1). |
Additional Info
| Function | Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. Together with dynein may be involved in spindle assembly and cytokinesis. |
| Protein Name | Dynactin Subunit 3Dynactin Complex Subunit 22 Kda SubunitP22 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-2565942Reactome: R-HSA-3371497Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-6807878Reactome: R-HSA-6811436Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeChromosomeCentromereKinetochoreSpindleCleavage FurrowMidbodyLocalizes To Punctate Cytoplasmic Structures And To The Centrosome During InterphaseAnd To Kinetochores And To Spindle Poles Throughout MitosisColocalizes With Dynein To The Cleavage Furrow And To Midbody Of Dividing Cells |
| Alternative Antibody Names | Anti-Dynactin Subunit 3 antibodyAnti-Dynactin Complex Subunit 22 Kda Subunit antibodyAnti-P22 antibodyAnti-DCTN3 antibodyAnti-DCTN22 antibody |
Information sourced from Uniprot.org