Anti-DUSP8 antibody (1-14) (STJ119964)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DUSP8 (1-14) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IF/ICC:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DUSP8 |
| Gene ID | 1850 |
| Uniprot ID | DUS8_HUMAN |
| Immunogen Region | 1-14 |
| Immunogen Sequence | MAGDRLPRKVMDAKKLASLL RGGPGGPLVIDSRSFVEYNS WHVLSSVNICCSKLVKRRLQ QGKVTIAELIQPAARSQVEA TEPQDVVVYDQSTRDASVLA |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DUSP8 (NP_004411.2). |
Additional Info
| Tissue Specificity | Abundant in brain, heart and skeletal muscle. |
| Function | Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues. |
| Protein Name | Dual Specificity Protein Phosphatase 8Dual Specificity Protein Phosphatase Hvh-5 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-5675221Reactome: R-HSA-9652817 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 8 antibodyAnti-Dual Specificity Protein Phosphatase Hvh-5 antibodyAnti-DUSP8 antibodyAnti-C11orf81 antibodyAnti-VH5 antibody |
Information sourced from Uniprot.org