Anti-DUSP8 antibody (1-14) (STJ119964)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ119964
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General Information

Short DescriptionRabbit polyclonal DUSP8 (1-14) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF/ICC/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:1000-1:5000
IF/ICC:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolDUSP8
Gene ID1850
Uniprot IDDUS8_HUMAN
Immunogen Region1-14
Immunogen SequenceMAGDRLPRKVMDAKKLASLL RGGPGGPLVIDSRSFVEYNS WHVLSSVNICCSKLVKRRLQ QGKVTIAELIQPAARSQVEA TEPQDVVVYDQSTRDASVLA
SpecificityA synthetic peptide corresponding to a sequence within amino acids 1-100 of human DUSP8 (NP_004411.2).

Additional Info

Tissue Specificity Abundant in brain, heart and skeletal muscle.
Function Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues.
Protein Name Dual Specificity Protein Phosphatase 8
Dual Specificity Protein Phosphatase Hvh-5
Database Links Reactome: R-HSA-112409
Reactome: R-HSA-5675221
Reactome: R-HSA-9652817
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Dual Specificity Protein Phosphatase 8 antibody
Anti-Dual Specificity Protein Phosphatase Hvh-5 antibody
Anti-DUSP8 antibody
Anti-C11orf81 antibody
Anti-VH5 antibody

Information sourced from Uniprot.org

Citations

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