Anti-DVL3 antibody (580-650) (STJ11103537)

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STJ11103537
£110.50 - £505.50
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Applications:WB/IHC-P/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:1000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:DVL3
Gene ID:1857
Uniprot ID:DVL3_HUMAN
Immunogen Region:580-650
Immunogen Sequence:RSGSDRRKEKDPKAGDSKSG GSGSESDHTTRSSLRGPRER APSERSGPAASEHSHRSHHS LASSLRSHHTH
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 580-650 of human DVL3 (NP_004414.3).
Post Translational Modifications Ubiquitinated. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains. Phosphorylated by CSNK1D. Arginine methylation may function as a switch in regulation of function in Wnt signaling.
Function Involved in the signal transduction pathway mediated by multiple Wnt genes.
Protein Name Segment Polarity Protein Dishevelled Homolog Dvl-3
Dishevelled-3
Dsh Homolog 3
Database Links Reactome: R-HSA-201681
Reactome: R-HSA-201688
Reactome: R-HSA-4086400
Reactome: R-HSA-4641258
Reactome: R-HSA-4641262
Reactome: R-HSA-5368598
Reactome: R-HSA-5663220
Reactome: R-HSA-9673324
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Segment Polarity Protein Dishevelled Homolog Dvl-3 antibody
Anti-Dishevelled-3 antibody
Anti-Dsh Homolog 3 antibody
Anti-DVL3 antibody
Anti-KIAA0208 antibody

Information sourced from Uniprot.org