| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DYNC1LI2 |
| Gene ID: | 1783 |
| Uniprot ID: | DC1L2_HUMAN |
| Immunogen Region: | 328-492 |
| Immunogen Sequence: | TTVKPEDAYEDFIVKPPVRK LVHDKELAAEDEQVFLMKQQ SLLAKQPATPTRASESPARG PSGSPRTQGRGGPASVPSSS PGTSVKKPDPNIKNNAASEG VLASFFNSLLSKKTGSPGSP GAGGVQSTAKKSGQKTVLSN VQEELDRMTRKPDSMVTNSS TENEA |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 328-492 of human DYNC1LI2 (NP_006132.1). |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. |
| Protein Name | Cytoplasmic Dynein 1 Light Intermediate Chain 2Dynein Light Intermediate Chain 2 - CytosolicLic-2Lic53/55 |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2132295Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-3371497Reactome: R-HSA-5663220Reactome: R-HSA-6807878Reactome: R-HSA-6811436Reactome: R-HSA-68877Reactome: R-HSA-9609690Reactome: R-HSA-9646399Reactome: R-HSA-9648025 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Cytoplasmic Dynein 1 Light Intermediate Chain 2 antibodyAnti-Dynein Light Intermediate Chain 2 - Cytosolic antibodyAnti-Lic-2 antibodyAnti-Lic53/55 antibodyAnti-DYNC1LI2 antibodyAnti-DNCLI2 antibodyAnti-LIC2 antibody |
Information sourced from Uniprot.org
