Anti-ELOVL1 antibody

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Product name Anti-ELOVL1 antibody
Description Rabbit polyclonal to ELOVL1.
Applications ELISA, WB
Dilution range WB 1:500-1:2000
ELISA 1:40000
Specificity ELOVL1 Polyclonal Antibody detects endogenous levels of ELOVL1 protein.
Protein Name Elongation of very long chain fatty acids protein 1
3-keto acyl-CoA synthase ELOVL1
ELOVL fatty acid elongase 1
ELOVL FA elongase 1
Very long chain 3-ketoacyl-CoA synthase 1
Very long chain 3-oxoacyl-CoA synthase 1
Immunogen Synthesized peptide derived from human ELOVL1
Immunogen Region 70-150 aa, Internal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Validated Application IHC WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 64834
Gene Symbol ELOVL1
Molecular Weight 35 kDa
Database Links HGNC:14418
Alternative Names Elongation of very long chain fatty acids protein 1 antibody
3-keto acyl-CoA synthase ELOVL1 antibody
ELOVL fatty acid elongase 1 antibody
ELOVL FA elongase 1 antibody
Very long chain 3-ketoacyl-CoA synthase 1 antibody
Very long chain 3-oxoacyl-CoA synthase 1 antibody
SSC1 antibody
CGI-88 antibody
Function Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity Ubiquitous.
Sequence and Domain Family The C-terminal di-lysine motif may confer endoplasmic reticulum localization.
Swiss-Prot Key Q9BW60_HUMAN
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