Anti-ENTPD6 antibody (61-300) (STJ118101)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ENTPD6 (61-300) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ENTPD6 |
| Gene ID | 955 |
| Uniprot ID | ENTP6_HUMAN |
| Immunogen Region | 61-300 |
| Immunogen Sequence | WHRATATQAFFSITRAAPGA RWGQQAHSPLGTAADGHEVF YGIMFDAGSTGTRVHVFQFT RPPRETPTLTHETFKALKPG LSAYADDVEKSAQGIRELLD VAKQDIPFDFWKATPLVLKA TAGLRLLPGEKAQKLLQKVK EVFKASPFLVGDDCVSIMNG TDEGVSAWITINFLTGSLKT PGGSSVGMLDLGGGSTQIAF LPRVEGTLQASPPGYLTALR MFNRTYKLYSYSYLGLGLM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 61-300 of human ENTPD6 (NP_001304870.1). |
Additional Info
| Tissue Specificity | Expressed in most tissues, but predominantly in heart. |
| Post Translational Modifications | The secreted form may be produced by intracellular processing. N-glycosylated. |
| Function | Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Has a strong preference for nucleoside diphosphates, preferentially hydrolyzes GDP, IDP, and UDP, with slower hydrolysis of CDP, ITP, GTP, CTP, ADP, and UTP and virtually no hydrolysis of ATP. The membrane bound form might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. |
| Protein Name | Ectonucleoside Triphosphate Diphosphohydrolase 6Ntpdase 6Cd39 Antigen-Like 2 |
| Database Links | Reactome: R-HSA-8850843 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinSecretedCell MembraneExists As A Secreted And Membrane-Bound Forms In The Medium Of Transfected CellsThe Secreted Form Is Predominant |
| Alternative Antibody Names | Anti-Ectonucleoside Triphosphate Diphosphohydrolase 6 antibodyAnti-Ntpdase 6 antibodyAnti-Cd39 Antigen-Like 2 antibodyAnti-ENTPD6 antibodyAnti-CD39L2 antibodyAnti-IL6ST2 antibody |
Information sourced from Uniprot.org