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Anti-ESA antibody [MOC‐31] (STJ180098)

Human colon adenocarcinoma stained with MOC-31 antibody using peroxidase-conjugate and DAB chromogen. Note the membranous staining of tumor cells.

Anti-ESA antibody [MOC‐31] (STJ180098)

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STJ180098

€190.63 - €638.13

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Host:	Mouse
Applications:	IHC-P
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-ESA is suitable for use in Immunohistochemistry research applications.

Clonality:	Monoclonal
Clone ID:	MOC‐31
Conjugation:	Unconjugated
Isotype:	IgG1/Kappa
Formulation:	Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification:	Affinity purified
Dilution Range:	1:100‐200
Storage Instruction:	Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.

Gene Symbol:	FLOT2
Gene ID:	2319
Uniprot ID:	FLOT2_HUMAN
Specificity:	Positive control: Colon carcinoma
Immunogen:	Neuraminidase treated GLS-1 human small cell lung carcinoma cells

Tissue Specificity	In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.
Post Translational Modifications	ZDHHC5-catalyzed palmitoylation predominantly occurs at Cys-4. ZDHHC5-catalyzed palmitoylation may be required for the formation of higher-order complexes and for neurite outgrowth in cultured neural stem cells.
Function	May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
Protein Name	Flotillin-2 Epidermal Surface Antigen Esa Membrane Component Chromosome 17 Surface Marker 1
Database Links	Reactome: R-HSA-5213460 Reactome: R-HSA-5675482 Reactome: R-HSA-8849932 Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106 Reactome: R-HSA-9696264 Reactome: R-HSA-9696273
Cellular Localisation	Cell Membrane Peripheral Membrane Protein Membrane Caveola Endosome Lipid-Anchor Membrane-Associated Protein Of Caveolae
Alternative Antibody Names	Anti-Flotillin-2 antibody Anti-Epidermal Surface Antigen antibody Anti-Esa antibody Anti-Membrane Component Chromosome 17 Surface Marker 1 antibody Anti-FLOT2 antibody Anti-ESA1 antibody Anti-M17S1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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