Anti-ESPL1 antibody (767-816 aa) (STJ95608)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SEPARASE at the amino acid range 767-816
General Information
| Short Description | Rabbit polyclonal anti-Separin (767-816 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ESPL1 |
| Gene ID | 9700 |
| Uniprot ID | ESPL1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human SEPARASE at the amino acid range 767-816 |
| Immunogen Region | 767-816 aa |
| Specificity | Separase Polyclonal Antibody detects endogenous levels of Separase protein. |
Additional Info
| Function | Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms. |
| Protein Name | SeparinCaspase-Like Protein Espl1Extra Spindle Poles-Like 1 ProteinSeparase |
| Database Links | Reactome: R-HSA-2467813 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Separin antibodyAnti-Caspase-Like Protein Espl1 antibodyAnti-Extra Spindle Poles-Like 1 Protein antibodyAnti-Separase antibodyAnti-ESPL1 antibodyAnti-ESP1 antibodyAnti-KIAA0165 antibody |
Information sourced from Uniprot.org