Anti-ETFB antibody (80-230) (STJ118483)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ETFB (80-230) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ETFB |
| Gene ID | 2109 |
| Uniprot ID | ETFB_HUMAN |
| Immunogen Region | 80-230 |
| Immunogen Sequence | AMGADRGIHVEVPPAEAERL GPLQVARVLAKLAEKEKVDL VLLGKQAIDDDCNQTGQMTA GFLDWPQGTFASQVTLEGDK LKVEREIDGGLETLRLKLPA VVTADLRLNEPRYATLPNIM KAKKKKIEVIKPGDLGVDLT SKLSVISVEDP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 80-230 of human ETFB (NP_001976.1). |
Additional Info
| Tissue Specificity | Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas. |
| Post Translational Modifications | Methylated. Trimethylation at Lys-200 and Lys-203 may negatively regulate the activity in electron transfer from acyl-CoA dehydrogenases. |
| Function | Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role. |
| Protein Name | Electron Transfer Flavoprotein Subunit BetaBeta-Etf |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-8876725 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Electron Transfer Flavoprotein Subunit Beta antibodyAnti-Beta-Etf antibodyAnti-ETFB antibodyAnti-FP585 antibody |
Information sourced from Uniprot.org