| Short Description : | Rabbit polyclonal anti-Fc receptor-like protein 5 (191-240 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FCRL5 |
| Gene ID: | 83416 |
| Uniprot ID: | FCRL5_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human FCRL5 at the amino acid range 191-240 |
| Immunogen Region: | 191-240 aa |
| Specificity: | CD307 Polyclonal Antibody detects endogenous levels of CD307 protein. |
| Function | Plays an important role in B-cell response to antigen that acts both as a negative or positive coreceptor. Inhibits B-cell receptor (BCR) signaling in the absence of CR2 stimulation but engagement with CR2 and the BCR lead to a superior calcium response compared to CR2 and BCR costimulation. May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. May play a role in fertilization. |
| Protein Name | Fc Receptor-Like Protein 5Fcr-Like Protein 5Fcrl5Bxmas1Fc Receptor Homolog 5Fcrh5Immune Receptor Translocation-Associated Protein 2Cd Antigen Cd307e |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Fc Receptor-Like Protein 5 antibodyAnti-Fcr-Like Protein 5 antibodyAnti-Fcrl5 antibodyAnti-Bxmas1 antibodyAnti-Fc Receptor Homolog 5 antibodyAnti-Fcrh5 antibodyAnti-Immune Receptor Translocation-Associated Protein 2 antibodyAnti-Cd Antigen Cd307e antibodyAnti-FCRL5 antibodyAnti-FCRH5 antibodyAnti-IRTA2 antibodyAnti-UNQ503 antibodyAnti-PRO820 antibody |
Information sourced from Uniprot.org
