Anti-FXYD5 antibody (22-145 aa) (STJ11107438)

SKU:
STJ11107438
€140.63 - €655.63
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: FXYD5
Gene ID: 53827
Uniprot ID: FXYD5_HUMAN
Immunogen Region: 22-145 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 22-145 of human FXYD5 (NP_054883.3).
Immunogen Sequence: QTLKDTTSSSSADSTIMDIQ VPTRAPDAVYTELQPTSPTP TWPADETPQPQTQTQQLEGT DGPLVTDPETHKSTKAAHPT DDTTTLSERPSPSTDVQTDP QTLKPSGFHEDDPFFYDEHT LRKR
Post Translational Modifications Glycosylated.
Function Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. May increase NKA activity by increasing the apparent affinity for Na(+). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis.
Protein Name Fxyd Domain-Containing Ion Transport Regulator 5
Dysadherin
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Basolateral Cell Membrane
In Kidneys Localizes To The Basolateral Membrane Of The Connecting Tubule
Alternative Antibody Names Anti-Fxyd Domain-Containing Ion Transport Regulator 5 antibody
Anti-Dysadherin antibody
Anti-FXYD5 antibody
Anti-DYSAD antibody
Anti-IWU1 antibody
Anti-HSPC113 antibody
Anti-UNQ2561 antibody
Anti-PRO6241 antibody

Information sourced from Uniprot.org