Anti-GABBR1 Antibody

[STJ112528] Download PDF Print Data Sheet

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Product name Anti-GABBR1 Antibody
Short Description Rabbit polyclonal against GABBR1
Description This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined.
Applications WB
Dilution range WB 1:1000 - 1:2000
Protein Name Gamma-aminobutyric acid type B receptor subunit 1
GABA-B receptor 1
GABA-B-R1
GABA-BR1
GABABR1
Gb1
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 200-460 of human GABBR1 (NP_068703.1).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 2550
Gene Symbol GABBR1
Molecular Weight 108.32 kDa
Database Links HGNC:4070
OMIM:603540
Reactome:R-HSA-1296041
Alternative Names Gamma-aminobutyric acid type B receptor subunit 1
GABA-B receptor 1
GABA-B-R1
GABA-BR1
GABABR1
Gb1
Function Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2 ,
Cellular Localization Cell membrane,
Tissue Specificity Highly expressed in brain
Swiss-Prot Key Q9UBS5
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