• Western blot analysis of extracts of various cell lines, using GABRA6 antibody (STJ114623) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 10s.

Anti-GABRA6 antibody (344-453) (STJ114623)

SKU:
STJ114623

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GABRA6 (344-453) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GABRA6
Gene ID: 2559
Uniprot ID: GBRA6_HUMAN
Immunogen Region: 344-453
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 344-453 of human GABRA6 (NP_000802.2).
Immunogen Sequence: PPTVTISKATEPLEAEIVLH PDSKYHLKKRITSLSLPIVS SSEANKVLTRAPILQSTPVT PPPLSPAFGGTSKIDQYSRI LFPVAFAGFNLVYWVVYLSK DTMEVSSSVE
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Protein Name Gamma-Aminobutyric Acid Receptor Subunit Alpha-6
Gaba(A Receptor Subunit Alpha-6
Database Links Reactome: R-HSA-977443
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Gamma-Aminobutyric Acid Receptor Subunit Alpha-6 antibody
Anti-Gaba(A Receptor Subunit Alpha-6 antibody
Anti-GABRA6 antibody

Information sourced from Uniprot.org

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